Disease Management  via ID Vaccination

The MSD Animal Health Porcilis® intradermal vaccine range can protect against common diseases caused by:

Porcine Circovirus Type 2 (PCV2)
Mesomycoplasma hyopneumoniae (M. hyo)
Lawsonia intracellularis (Lawsonia)
Porcine Reproductive & Respiratory Syndrome (PRRS)

As we launch our newest member of the IDAL™ vaccine family, let’s take a deep dive into PCV2 and M. hyo.

Porcine Circovirus Type 2 (PCV2) and Mesomycoplasma hyopneumoniae (M. hyo)

Porcine Circovirus Type 2 (PCV2) and Mesomycoplasma hyopneumoniae (M. hyo) are infectious agents causing two of the top five diseases impacting swine production.

M. hyo is the primary initiator of Enzootic Pneumonia (EP), a chronic respiratory disease which can be associated with:

A dry and  non-productive cough

High morbidity rates

A negative effect on average daily gain and feed conversion ratio

Amplification of the severity of other infections, including flu, PRRS and PCV2

A dry and  non-productive cough

A high  morbidity  rate

A strong effect on the average daily gain and feed conversion ratio

Amplification of the severity of other infections, including flu, PRRS and PCV2

PCV2 causes porcine circovirosis. Clinically, it presents as a disease which causes wasting from the weaning to the finishing period. Characteristics include:

Immunosuppression
Strong environmental resistance
Potential for high mortality

Concurrent infection with PCV2 and M. hyo causes:

Severe respiratory disease
Lesions consistent with Porcine Respiratory Disease Complex (PRDC)

Economic impact of disease

PCV2 has an enormous impact on productivity, with mortality ranging from 4% to 20%. Before implementation of preventive measures, the cost of the disease for the EU was estimated to be between €562 and €900 million per year.¹

Economic losses associated with PCV2 and M. hyo are a consequence of:

Increased mortality and culls
Reduced growth rates with an overall worsening of production parameters (ADWG, FCR)
Increased cost for management and medication of sick pigs
Increased costs as a result of secondary diseases

Disease prevalence of PCV2 and M. hyo in most European countries…

13-70%

Reported prevalence of lung lesions compatible with M. hyo at the slaughterhouse.

66%

The mean M. hyo herd prevalence in finishing pigs estimated by PCR testing.

50-60%

of pigs within the herd affected by PCV2.

References

Alarcon P, Rushton J, Wieland B. Cost of post-weaning multi-systemic wasting syndrome and porcine circovirus type-2 subclinical infection in England – an economic disease model. Prev Vet Med. 2013;110(2):88-102. doi:10.1016/j.prevetmed.2013.02.010
Boeters M, Garcia-Morante B, van Schaik G, Segalés J, Rushton J, Steeneveld W. The economic impact of endemic respiratory disease in pigs and related interventions – a systematic review. Porcine Health Manag. 2023;9(1):45. Published 2023 Oct 17. doi:10.1186/s40813-023-00342-w
Pallarés FJ, Añón JA, Rodríguez-Gómez IM, et al. Prevalence of mycoplasma-like lung lesions in pigs from commercial farms from Spain and Portugal. Porcine Health Manag. 2021;7(1):26. Published 2021 Mar 8. doi:10.1186/s40813-021-00204-3
Hillen S, von Berg S, Köhler K, Reinacher M, Willems H, Reiner G. Occurrence and severity of lung lesions in slaughter pigs vaccinated against Mycoplasma hyopneumoniae with different strategies. Prev Vet Med. 2014;113(4):580-588. doi:10.1016/j.prevetmed.2013.12.012
Paz-Sánchez Y, Herráez P, Quesada-Canales Ó, et al. Assessment of Lung Disease in Finishing Pigs at Slaughter: Pulmonary Lesions and Implications on Productivity Parameters. Animals (Basel). 2021;11(12):3604. Published 2021 Dec 20. doi:10.3390/ani11123604
Przyborowska-Zhalniarovich P, Maes D, Otrocka-Domagała I, Paździor-Czapula K, Wiszniewska-Łaszczych A, Sołtysiuk M. Association between Enzootic Pneumonia-like Lung Lesions and Carcass Quality and Meat pH Value in Slaughter Pigs. Animals (Basel). 2023;13(13):2210. Published 2023 Jul 5. doi:10.3390/ani13132210

Disease Management via ID Vaccination